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English Name: | Loperamide Hydrochloride | CAS:: | 34552-83-5 |
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MF:: | C29H34Cl2N2O2 | EINECS:: | 252-082-4 |
Other Name:: | Loperamide HCl; Lopemid; LoperaMide Hydrochloride; Imodium; 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide,hydrochloride; | Appearance:: | White Crystal |
Application:: | Long-acting Anti-diarrhea Medicines | Purity:: | >99% |
PSA:: | 43.78000 | LogP:: | 5.82790 |
High Light: | pharmaceutical industry raw materials,medicine raw material |
Loperamide Hydrochloride Digestive System Long-acting Anti-diarrhea Medicine CAS 34552-83-5
Product Name: | Loperamide hydrochloride |
Synonyms: | lopemid;lopemin;loperyl;pj185;r18553;suprasec;Loperamide hydrochloride, Vetranal;LOPERAMIDE HYDROCHLROIDE |
CAS: | 34552-83-5 |
MF: | C29H34Cl2N2O2 |
MW: | 513.5 |
EINECS: | 252-082-4 |
Product Categories: | ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;IMODIUM;Other APIs |
Mol File: | 34552-83-5.mol |
Loperamide hydrochloride Chemical Properties |
Melting point | 223-225°C |
density | 1.1905 (rough estimate) |
refractive index | 1.6100 (estimate) |
storage temp. | Store at RT |
solubility | Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol. |
form | neat |
pka | 8.66(at 25℃) |
Merck | 14,5571 |
CAS DataBase Reference | 34552-83-5(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | TM4960000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29333990 |
Toxicity | LD50 in mice (mg/kg): 75 s.c.; 28 i.p.; 105 orally; in rats (mg/kg): 185 orally (Niemegeers) |
Loperamide hydrochloride Usage And Synthesis |
Chemical Properties | White Solid |
Uses |
1. Long-acting anti-diarrhea drugs for the treatment of acute and chronic dysentery, which can be used to produce captopyramine hydrochloride capsules.
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