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100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9

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100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9

China 100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9 supplier
100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9 supplier 100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9 supplier 100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9 supplier

Large Image :  100% Non - Steroidal Anti - Inflammatory Analgesics Lornoxicam CAS 70374-39-9

Product Details:

Place of Origin: china
Brand Name: Lornoxicam
Certification: GMP
Model Number: pr-1255

Payment & Shipping Terms:

Minimum Order Quantity: 0.5 kg
Price: Negotiable
Packaging Details: 10kg/ bag
Delivery Time: 3~5 week days
Payment Terms: Western Union, T/T, MoneyGram,
Supply Ability: 10000kg/month
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Detailed Product Description
English Name: Lornoxicam CAS:: 70374-39-9
MF:: C13H10ClN3O4S2 EINECS:: 630-354-7
Other Name:: Chlortenoxicam; Telos; Lorcam; 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide; Xefocam; Appearance:: Faint Yellow To Dark Yellow Solid Powder
Application:: Treatment Of Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Gouty Arthritis And Tenosynovitis Purity:: >99%
PSA:: 136.22000 LogP:: 3.38760
Grade Standard: Medicine Grade
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100% Non-steroidal Anti-inflammatory Analgesics Lornoxicam CAS:70374-39-9
 

Product Name: Lornoxicam
Synonyms: LORNOXICAM;AKOS 93662;6-Chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide;LornoxicaM for injection;6-Chloro-4-hydroxy-2-Methyl-N-2-pyridinyl-;LornoxicaM API;6-CHLORO-4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;2h-thieno(2,3-e)-1,2-thiazine-3-carboxamide,6-chloro-4-hydroxy-2-methyl-n-2-py
CAS: 70374-39-9
MF: C13H10ClN3O4S2
MW: 371.82
EINECS: 630-354-7
Product Categories: API;AVITA;APIs;Inhibitors;Intermediates & Fine Chemicals;Other APIs;Pharmaceuticals;Sulfur & Selenium Compounds;Fused Ring Systems
Mol File: 70374-39-9.mol
Lornoxicam Structure
 
Lornoxicam Chemical Properties
Melting point 225-230°C (dec.)
storage temp. -20°C Freezer
solubility DMSO: >5mg/mL (warmed)
pka pKa2 4.7(at 25℃)
form powder
color faint yellow to dark yellow
Merck 14,5582
CAS DataBase Reference 70374-39-9(CAS DataBase Reference)
 
Safety Information
Hazard Codes Xi,T+
Risk Statements 36/37/38-28
Safety Statements 26-36-45-36/37-28
RIDADR UN 2811 6.1 / PGII
WGK Germany 3
RTECS XJ9095000
HazardClass IRRITANT
PackingGroup II
HS Code 29349990
Toxicity LD50 orally in mice, rats, rabbits, dogs, monkeys: >10 mg/kg (Pruss)
 
MSDS Information
 
 
Lornoxicam Usage And Synthesis
Description Lornoxicam (Trade name: “Xefo”) belongs to a non-steroidal anti-inflammatory drug. As a kind of oxicam class drug, it has analgesic, anti-inflammatory and antipyretic properties. It can be used for the treatment of various type of acute mild to moderate pain which results from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and rheumatic diseases. Lornoxicam is capable of potently inhibiting the prostaglandin biosynthesis process, making it have highly pronounced efficacy. The exact mechanism of Lornoxicam is not exactly understood. However, it is indicated that Lornoxicam can inhibit the prostaglandin and thromboxane synthesis by inhibiting both COX-1 and COX-2, leading to reduction of inflammation, pain, fever, and swelling.
References https://www.drugbank.ca/drugs/DB06725
https://en.wikipedia.org/wiki/Lornoxicam
Chemical Properties Crystalline Solid
Uses keratolytic, antiacne, antineoplastic
Uses ocular vasoconstrictor
Uses For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
Uses Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic

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