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Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker

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Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker

China Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker supplier
Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker supplier Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker supplier Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker supplier

Large Image :  Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker

Product Details:

Place of Origin: china
Brand Name: famotidine
Certification: GMP
Model Number: pr-1155

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 25kg/ bag
Delivery Time: 3~5 week days
Payment Terms: Western Union, T/T, MoneyGram,
Supply Ability: 10000kg/month
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Detailed Product Description
English Name: Famotidine CAS:: 76824-35-6
MF:: C8H15N7O2S3 EINECS:: 616-396-9
Other Name:: Ifada; Gaster; Famotidine; Fibonel; Appearance:: White Solid
Application:: Histamine H2 Receptor Blocker Purity:: >99%
PSA:: 235.25000 LogP:: 3.11400
Grade Standard: Medicine Grade

Pharmaceutical Intermediates Famotidine CAS 76824-35-6 Histamine H2 Receptor Blocker

 

Product Name: Famotidine
Synonyms: aminosulfonyl)-;dispronil;famodil;famosan;famoxal;fanosin;fibonel;ganor
CAS: 76824-35-6
MF: C8H15N7O2S3
MW: 337.45
EINECS: 616-396-9
Product Categories: Histamine receptor;Amines;Heterocycles;Sulfur & Selenium Compounds;LODINE;Other APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API's
Mol File: 76824-35-6.mol
Famotidine Structure
 
Famotidine Chemical Properties
Melting point 163-164°C
density 1.5111 (rough estimate)
refractive index 1.7400 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Very slightly soluble in water, freely soluble in glacial acetic acid, very slightly soluble in anhydrous ethanol, practically insoluble in ethyl acetate. It dissolves in dilute mineral acids
form neat
pka pKa 6.76(H2O t=23.0) (Uncertain)
Water Solubility 1.1 mg/mL
InChIKey XUFQPHANEAPEMJ-UHFFFAOYSA-N
CAS DataBase Reference 76824-35-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes T
Risk Statements 20/21/22-45-61
Safety Statements 22-24/25-53-45-36/37/39
WGK Germany 2
RTECS UA2300000
HS Code 29341000
Hazardous Substances Data 76824-35-6(Hazardous Substances Data)
Toxicity LD50 i.v. in mice: 244.4 mg/kg (Yasufumi)
 
MSDS Information
Provider Language
Famotidine English
SigmaAldrich English
 
Famotidine Usage And Synthesis
Description Famotidine (Chemical formula: C8H15N7O2S3; Brand Name: PEPCID) belongs to a histamine H2-receptor antagonist. It appears as a white to pale yellow crystalline compound. Inside the body, its primary activity is inhibiting the gastric secretion process, further reducing the acid concentration and volume of gastric secretion in the stomach. Based on this property, it is used for the treatment and prevention of ulcers occurring in the stomach and intestines. It can also treat diseases such as Zollinger-Ellison syndrome in which the stomach accumulates excess amount of acids. Moreover, it is also applied during the treatment of gastroesophageal reflux disease (GERD) and pathological hypersecretory conditions.
Reference http://www.rxlist.com/pepcid-drug/clinical-pharmacology.htm
https://en.wikipedia.org/wiki/Famotidine
Description Famotidine is a competitive histamine H2-receptor antagonist, and the main pharmacodynamic effect of famotidine is to cause the inhibition of gastric secretion. Famotidine on decomposition releases toxic products such as carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), and sulphur oxides (SO2, SO3). Famotidine is a medication that is available both in prescription and over-the-counter forms. It is used to treat conditions related to the oesophagus, stomach, and intestines. Some specific famotidine is used for the treatment of duodenal ulcers, gastric ulcers (stomach ulcers), gastroesophageal reflux disease (GERD), and pathological hypersecretory conditions that occur when stomach acid is secreted/ produced in very large quantities, an abnormal health condition called ‘Zollinger-Ellison syndrome’.
Chemical Properties White Powder
Uses Histamine H2-receptor antagonist. Antiulcerative.
Uses antiinflammatory
Uses For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Uses Use as an H2-antagonist. An anti-ulcer agent

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